Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CFTR | P13569 | 2/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15049094 | 0.88 | TRPM8 (0.56) | MAPTHPGDTSHRTP53LMNA | |
| SCHEMBL27997076 | 0.84 | CDC7 (0.52) | — | |
| SCHEMBL28245727 | 0.79 | CYP1A2 (0.48) | LMNACLK4PDE5AALDH1A1 | |
| SCHEMBL15049469 | 0.75 | TRPM8 (0.50) | MAPTTP53LMNAALDH1A1 | |
| SCHEMBL15049531 | 0.72 | CDC7 (0.73) | MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL3933679 | 0.72 | CLK4 (0.59) | MAPTHPGDTSHRLMNACLK1 | |
| SCHEMBL1946452 | 0.70 | FYN (0.73) | MAPTHPGDTSHRCLK1CLK4 | |
| SCHEMBL15049019 | 0.68 | TRPM8 (0.77) | ALDH1A1 | |
| SCHEMBL3436646 | 0.67 | SMN1; SMN2 (0.70) | MAPTHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL4174800 | 0.67 | KDR (0.51) | MAPTHPGDTSHRMAP2K4CLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104220069-B | Trpm8 antagonists | 多姆皮制药公司 | 2018-10-02 | — | — | CN | claimed |
| CN-104220069-B | Trpm8 antagonists | 多姆皮制药公司 | 2018-10-02 | — | — | CN | disclosed |