Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 20/20 | 0.74 |
| ▸ | SLC6A2 | P23975 | 14/20 | 0.74 |
| ▸ | SLC6A3 | Q01959 | 18/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15862815 | 0.96 | SLC6A4 (0.74) | SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL10878340 | 0.92 | SLC6A4 (0.69) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL14314489 | 0.86 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL3467709 | 0.82 | SLC6A4 (0.80) | SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL3467707 | 0.82 | SLC6A4 (0.80) | SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL1566412 | 0.82 | SLC6A4 (0.74) | SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL6169426 | 0.82 | SLC6A4 (0.58) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL3518627 | 0.81 | SLC6A3 (1.00) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL14314490 | 0.81 | SLC6A4 (0.80) | SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL5085593 | 0.81 | SLC6A4 (0.72) | SLC6A4SLC6A2SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104254522-A | Methanol derivatives as trpv3 modulators | ABBVIE INC | 2014-12-31 | — | — | CN | disclosed |