Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 20/20 | 0.72 |
| ▸ | SLC6A3 | Q01959 | 18/20 | 0.72 |
| ▸ | SLC6A2 | P23975 | 17/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1566412 | 0.98 | SLC6A4 (0.74) | SLC6A4SLC6A3SLC6A2CYP2D6 | |
| SCHEMBL9027256 | 0.85 | SLC6A4 (0.80) | SLC6A4SLC6A3SLC6A2CYP2D6 | |
| SCHEMBL15862815 | 0.84 | SLC6A4 (0.74) | SLC6A4SLC6A3SLC6A2CYP2D6 | |
| SCHEMBL8458076 | 0.84 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2CYP2D6 | |
| SCHEMBL15043689 | 0.83 | SLC6A4 (0.66) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL5085612 | 0.83 | SLC6A3 (0.76) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL1981733 | 0.82 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2CYP2D6 | |
| SCHEMBL1981732 | 0.82 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2CYP2D6 | |
| SCHEMBL3466313 | 0.82 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2CYP2D6 | |
| SCHEMBL27997201 | 0.81 | SLC6A4 (0.74) | SLC6A4SLC6A3SLC6A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1976513-A2 | CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS | Sepracor, Inc. (US) | 2008-10-08 | — | — | EP | disclosed |
| WO-2007081857-A2 | CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS | SEPRACOR INC. (US) | 2007-07-19 | — | — | WO | disclosed |