Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26103588 | 0.81 | MYC (0.49) | MYCSMN1; SMN2KMT2AL3MBTL1MEN1 | |
| SCHEMBL15630880 | 0.79 | DPP4 (0.51) | MYCSMN1; SMN2KMT2AMEN1POLB | |
| SCHEMBL2069663 | 0.79 | DPP4 (0.51) | MYCSMN1; SMN2KMT2AMEN1POLB | |
| SCHEMBL5742226 | 0.79 | MYC (0.55) | MYCSMN1; SMN2KMT2AL3MBTL1MEN1 | |
| SCHEMBL27685972 | 0.78 | MYC (0.46) | MYCSMN1; SMN2KMT2AL3MBTL1MEN1 | |
| SCHEMBL29232403 | 0.77 | MYC (0.54) | MYCSMN1; SMN2KMT2AL3MBTL1MEN1 | |
| SCHEMBL6828910 | 0.77 | ALDH1A1 (0.50) | MYCSMN1; SMN2KMT2AL3MBTL1MEN1 | |
| SCHEMBL28562172 | 0.77 | MYC (0.50) | MYCSMN1; SMN2KMT2AL3MBTL1MEN1 | |
| SCHEMBL28989185 | 0.77 | MYC (0.50) | MYCSMN1; SMN2KMT2AL3MBTL1MEN1 | |
| SCHEMBL28989191 | 0.76 | MYC (0.49) | MYCSMN1; SMN2KMT2AL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104271576-A | Pyridopyrimidinone inhibitors of kinases | ABBVIE INC | 2015-01-07 | — | — | CN | disclosed |