SCHEMBL27997641

SCHEMBL27997641

c1ccc2c(-c3ncnc4nccnc34)cccc2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PI4KA P42356 1/20 0.43
PI4K2B Q8TCG2 1/20 0.43
PI4K2A Q9BTU6 1/20 0.43
PI4KB Q9UBF8 1/20 0.43
ALDH1A1 P00352 4/20 0.43
MAPT P10636 4/20 0.43
HPGD P15428 3/20 0.43
KDM4E B2RXH2 2/20 0.43
HSD17B10 Q99714 2/20 0.43
GAA P10253 1/20 0.43
BCHE P06276 2/20 0.42
GSK3B P49841 1/20 0.40
CDK5 Q00535 1/20 0.40
CDK5R1 Q15078 1/20 0.40
PRKD3 O94806 2/20 0.39
PRKD1 Q15139 2/20 0.39
PRKD2 Q9BZL6 2/20 0.39
RIPK2 O43353 1/20 0.39
ABL1 P00519 1/20 0.39
FYN P06241 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27997637 0.83 CYP11B1 (0.41) PI4KAPI4K2BPI4K2API4KBALDH1A1
SCHEMBL17508371 0.78 ALDH1A1 (0.41) ALDH1A1MAPTHPGDKDM4EHSD17B10
SCHEMBL27997397 0.77 SMN1; SMN2 (0.44) ALDH1A1HPGDKDM4ESMN1; SMN2NPC1
SCHEMBL15901793 0.77 BCHE (0.57) ALDH1A1MAPTHPGDKDM4EHSD17B10
SCHEMBL13078965 0.73 GSK3B (0.47) ALDH1A1MAPTHPGDKDM4EHSD17B10
SCHEMBL18731747 0.73 ADORA2A (0.56) PI4KAPI4K2BPI4K2API4KBALDH1A1
SCHEMBL29986658 0.73 ADORA2A (0.56) PI4KAPI4K2BPI4K2API4KBALDH1A1
SCHEMBL27997621 0.72 ADORA2A (0.46) ALDH1A1MAPTHPGDKDM4EHSD17B10
SCHEMBL27997390 0.71 MAPK9 (0.49) KDM4EABL1SRCMAPK8NISCH
SCHEMBL23946254 0.71 LIMK1 (0.44) PI4KAPI4K2BPI4K2API4KBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104725369-A Binary phenothiazine imidazole derivative, preparation method and organic light emitting device JILIN OPTICAL & ELECTRONIC MATERIALS CO LTD 2015-06-24 CN disclosed