Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27997641 | 0.77 | PI4KA (0.43) | SMN1; SMN2MAPK14MAPK11NPC1RAB9A | |
| SCHEMBL27997621 | 0.74 | ADORA2A (0.46) | SMN1; SMN2TP53HPGDALDH1A1KDM4E | |
| SCHEMBL27997637 | 0.72 | CYP11B1 (0.41) | SMN1; SMN2TP53HPGDALDH1A1KDM4E | |
| SCHEMBL17508366 | 0.71 | ADORA2A (0.43) | SMN1; SMN2MAPK14TP53HPGDALDH1A1 | |
| SCHEMBL29985972 | 0.68 | SMN1; SMN2 (0.67) | SMN1; SMN2SIGMAR1RAB9AALDH1A1KDM4E | |
| SCHEMBL6338383 | 0.68 | SMN1; SMN2 (0.67) | SMN1; SMN2SIGMAR1RAB9AALDH1A1KDM4E | |
| SCHEMBL17508367 | 0.68 | PIK3CG (0.40) | MAPK14MAPK13MAPK12MAPK11 | |
| Benzene SCHEMBL2213570 | 0.67 | PDE4A (0.34) | SMN1; SMN2 | |
| SCHEMBL20821396 | 0.67 | DPP4 (0.65) | SMN1; SMN2DPP4CYP2A6NPC1RAB9A | |
| SCHEMBL1915790 | 0.67 | DPP4 (0.54) | SMN1; SMN2DPP4CYP2A6NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104725369-B | Phenthazine containing binary and imidazole derivative, preparation method and organic luminescent device | 吉林奥来德光电材料股份有限公司 | 2017-11-21 | — | — | CN | disclosed |
| CN-104725369-A | Binary phenothiazine imidazole derivative, preparation method and organic light emitting device | JILIN OPTICAL & ELECTRONIC MATERIALS CO LTD | 2015-06-24 | — | — | CN | disclosed |