SCHEMBL27998908

SCHEMBL27998908

CCC(C(C)=O)c1ccc(C)c2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.43
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
CNR2 P34972 4/20 0.36
CNR1 P21554 1/20 0.36
ALDH1A1 P00352 2/20 0.35
CYP2A6 P11509 1/20 0.34
LMNA P02545 1/20 0.34
HSD17B10 Q99714 1/20 0.34
GAA P10253 2/20 0.33
KDM4E B2RXH2 2/20 0.33
HPGD P15428 1/20 0.33
MAPT P10636 1/20 0.33
PABPC1 P11940 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MCL1 Q07820 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19145987 0.77 CYP1A2 (0.48) CYP1A2CNR2CNR1ALDH1A1CYP2A6
SCHEMBL28816574 0.73 CYP1A2 (0.43) CYP1A2CNR2CNR1ALDH1A1CYP2A6
SCHEMBL11054382 0.73 TSHR (0.50) CYP1A2MEN1KMT2AALDH1A1LMNA
SCHEMBL7823512 0.73 CYP1A2 (0.52) CYP1A2CNR2CNR1ALDH1A1CYP2A6
SCHEMBL27851962 0.72 CYP1A2 (0.50) CYP1A2CNR2CNR1ALDH1A1CYP2A6
SCHEMBL11054288 0.70 CYP1A2 (0.48) CYP1A2ALDH1A1CYP2A6LMNAKDM4E
SCHEMBL7007166 0.69 CYP1A2 (0.65) CYP1A2MEN1KMT2AALDH1A1CYP2A6
SCHEMBL13389213 0.69 LMNA (0.58) MEN1KMT2AALDH1A1LMNAHSD17B10
SCHEMBL13020177 0.69 LMNA (0.58) MEN1KMT2AALDH1A1LMNAHSD17B10
SCHEMBL12061479 0.69 CYP1A2 (0.56) CYP1A2ALDH1A1CYP2A6LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104370715-B A kind of synthetic method of alpha-aromatic ketone compound DALIAN UNIVERSITY OF TECHNOLOGY (CN) 2015-10-28 CN disclosed
CN-104370715-A Synthesis method of alpha-aryl ketone compound UNIV DALIAN TECH 2015-02-25 CN disclosed