Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA7 | P43166 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13724561 | 0.86 | ALDH1A1 (0.50) | SMN1; SMN2CA1CA2CA7CA9 | |
| SCHEMBL4132573 | 0.83 | SRC (0.58) | CA1CA2ALDH1A1KDM4ELMNA | |
| SCHEMBL4553620 | 0.79 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1MAPK1TP53MAPT | |
| SCHEMBL9527314 | 0.79 | CA1 (0.62) | CA1CA2CA7CA9CA12 | |
| SCHEMBL30041663 | 0.79 | CA1 (0.62) | CA1CA2CA7CA9CA12 | |
| SCHEMBL24926176 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2CA1CA2CA7CA9 | |
| SCHEMBL27451265 | 0.78 | CA12 (0.42) | SMN1; SMN2CA1CA2CA7CA9 | |
| SCHEMBL18246053 | 0.77 | ALDH1A1 (0.43) | CA1CA2CA7CA9CA12 | |
| SCHEMBL11749913 | 0.76 | SMN1; SMN2 (0.47) | SMN1; SMN2CA1CA2CA7CA9 | |
| SCHEMBL19612192 | 0.76 | SMN1; SMN2 (0.47) | SMN1; SMN2CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102869355-B | Pde10 inhibitors and related compositions and methods | OMEROS CORP | 2015-07-08 | — | — | CN | disclosed |
| CN-104710385-A | PDE10 inhibitors and related compositions and methods | OMEROS CORP | 2015-06-17 | — | — | CN | disclosed |