Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | SHBG | P04278 | 1/20 | 0.50 |
| ▸ | MDH1 | P40925 | 6/20 | 0.46 |
| ▸ | MDH2 | P40926 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | FYN | P06241 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7879426 | 1.00 | CYP3A4 (0.61) | CYP3A4SMN1; SMN2LMNASHBGMDH1 | |
| SCHEMBL10612296 | 0.93 | CYP3A4 (0.54) | CYP3A4SMN1; SMN2LMNASHBGMDH1 | |
| SCHEMBL15677164 | 0.84 | AR (0.62) | CYP3A4SMN1; SMN2LMNASHBGMDH1 | |
| SCHEMBL2108184 | 0.84 | CYP3A4 (0.62) | CYP3A4SMN1; SMN2LMNASHBGMDH1 | |
| SCHEMBL2108647 | 0.83 | SMN1; SMN2 (0.54) | CYP3A4SMN1; SMN2LMNASHBGMDH1 | |
| SCHEMBL17024108 | 0.83 | CYP3A4 (0.56) | CYP3A4SMN1; SMN2LMNASHBGMDH1 | |
| SCHEMBL2044174 | 0.82 | LMNA (0.60) | SMN1; SMN2LMNAHTTHIF1AMAPT | |
| SCHEMBL13792030 | 0.82 | LMNA (0.60) | SMN1; SMN2LMNAHTTHIF1AMAPT | |
| SCHEMBL376300 | 0.82 | HIF1A (0.61) | SMN1; SMN2LMNAHTTHIF1AMAPT | |
| SCHEMBL15677151 | 0.80 | SMN1; SMN2 (0.54) | CYP3A4SMN1; SMN2LMNASHBGMDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104447792-A | Substituted dihydro and tetrahydro oxazolopyrimidinones, preparation and use thereof | SANOFI AVENTIS | 2015-03-25 | — | — | CN | disclosed |