Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17199 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL28232772 | 0.82 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1935429 | 0.82 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3088467 | 0.82 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| Imidazole SCHEMBL6181652 | 0.71 | ALDH1A1 (0.54) | ALDH1A1FKBP5SMN1; SMN2 | |
| Imidazole SCHEMBL9175235 | 0.70 | — | — | |
| Imidazole SCHEMBL1331920 | 0.69 | — | — | |
| Imidazole SCHEMBL1331382 | 0.69 | — | — | |
| Imidazole SCHEMBL2635292 | 0.69 | — | — | |
| Imidazole SCHEMBL897 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104370909-A | Novel tricyclic compounds | ABBOTT LAB | 2015-02-25 | — | — | CN | disclosed |