Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imidazole SCHEMBL7479498 | 0.98 | ALDH1A1 (0.52) | ALDH1A1FKBP5SMN1; SMN2 | |
| SCHEMBL25231508 | 0.82 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL116 | 0.82 | — | — | |
| SCHEMBL2269935 | 0.79 | — | — | |
| SCHEMBL2271924 | 0.79 | — | — | |
| SCHEMBL2269360 | 0.79 | — | — | |
| SCHEMBL5506833 | 0.79 | — | — | |
| SCHEMBL2269356 | 0.79 | — | — | |
| Ammonia Solution, Strong SCHEMBL9403872 | 0.79 | — | — | |
| SCHEMBL10343352 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506187-A1 | 2-THIO-SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR USE IN PHARMACEUTICS | MERCKLE GMBH (DE) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003097633-A1 | 2-THIO-SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR USE IN PHARMACEUTICS | MERCKLE GMBH (DE) | 2003-11-27 | — | — | WO | disclosed |
| EP-0933364-B1 | Imidazolate sulfur difluorides | AIR PROD & CHEM (US) | 2002-05-02 | — | — | EP | disclosed |
| US-5939546-A | USEFUL DEOXOFLUORINATION REAGENTS | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1999-08-17 | — | — | US | disclosed |
| EP-0933364-A1 | Imidazolate sulfur difluorides | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1999-08-04 | — | — | EP | disclosed |