SCHEMBL28001024

SCHEMBL28001024

N=C(c1ccccc1)c1ccccc1.[Ni]

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 2/20 0.55
F10 P00742 1/20 0.55
F12 P00748 1/20 0.55
F7 P08709 1/20 0.55
F3 P13726 1/20 0.55
PKM P14618 1/20 0.55
BLM P54132 2/20 0.52
RECQL P46063 2/20 0.50
PRSS1 P07477 2/20 0.50
PRSS2 P07478 2/20 0.50
PRSS3 P35030 2/20 0.50
KMT2A Q03164 2/20 0.50
C1S P09871 1/20 0.50
CES1 P23141 4/20 0.45
TSHR P16473 3/20 0.45
CES2 O00748 2/20 0.45
DAO P14920 1/20 0.45
NAPRT Q6XQN6 1/20 0.45
ALDH1A1 P00352 1/20 0.45
CYP3A4 P08684 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16954 0.97 F2 (0.58) F2F10F12F7F3
SCHEMBL27411702 0.97 F2 (0.58) F2F10F12F7F3
Ammonia Solution, Strong SCHEMBL28070268 0.93 F2 (0.55) F2F10F12F7F3
SCHEMBL10607595 0.93 F2 (0.55) F2F10F12F7F3
Hydrochloric Acid SCHEMBL30040932 0.93 BLM (0.60) F2F10F12F7F3
SCHEMBL4578344 0.93 F2 (0.55) F2F10F12F7F3
Hydrochloric Acid SCHEMBL18795794 0.93 BLM (0.60) F2F10F12F7F3
SCHEMBL27279692 0.85 F2 (0.48) F2F10F12F7F3
Benzophenone SCHEMBL23175180 0.83 ALDH1A1 (0.74) KMT2ACES1TSHRCES2DAO
SCHEMBL10607839 0.83 CES2 (0.58) F2F10F12F7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104250270-B Asymmetric benzhydryl alpha-diimine nickel complex and preparation and application thereof 中国石油天然气股份有限公司 2017-02-15 CN disclosed
CN-104250270-A Asymmetric benzhydryl alpha-diimine nickel complex and preparation and application thereof PETROCHINA CO LTD 2014-12-31 CN disclosed
CN-104250270-A Asymmetric benzhydryl alpha-diimine nickel complex and preparation and application thereof PETROCHINA CO LTD 2014-12-31 CN disclosed