Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 8/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1820951 | 0.80 | ALDH1A1 (0.58) | ALDH1A1TDP1TSHRGRIN2DGRIN3B | |
| SCHEMBL8440730 | 0.78 | TSHR (0.58) | ALDH1A1TDP1TSHRCYP3A4KMT2A | |
| Formaldehyde SCHEMBL28712793 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TDP1TSHRGRIN2DGRIN3B | |
| SCHEMBL28420852 | 0.77 | ALDH1A1 (0.54) | ALDH1A1TDP1TSHRGRIN2DGRIN3B | |
| SCHEMBL487510 | 0.76 | ALDH1A1 (0.54) | ALDH1A1TDP1TSHRCYP3A4KMT2A | |
| SCHEMBL2493668 | 0.76 | ALDH1A1 (0.54) | ALDH1A1TDP1TSHRGRIN2DGRIN3B | |
| SCHEMBL540061 | 0.76 | ALDH1A1 (0.54) | ALDH1A1TDP1TSHRGRIN2DGRIN3B | |
| SCHEMBL3781263 | 0.76 | TSHR (0.60) | ALDH1A1TDP1TSHRGRIN2DGRIN3B | |
| SCHEMBL487041 | 0.76 | ALDH1A1 (0.54) | ALDH1A1TDP1TSHRGRIN2DGRIN3B | |
| SCHEMBL487063 | 0.76 | ALDH1A1 (0.54) | ALDH1A1TDP1TSHRGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104334540-B | Dimethyl-benzoic acid compounds | ELI LILLY AND CO. (US) | 2016-03-16 | — | — | CN | disclosed |
| CN-104334540-A | Dimethyl-Benzoic acid compounds | LILLY CO ELI | 2015-02-04 | — | — | CN | disclosed |