Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.49 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | CDC25A | P30304 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9264337 | 0.81 | SCN10A (0.54) | SCN10ASHMT2PIM1MAPTKDM4E | |
| SCHEMBL23367875 | 0.79 | SHMT2 (0.50) | SCN10ASHMT2PIM1MAPTALPI | |
| SCHEMBL2090191 | 0.78 | SHMT2 (0.56) | SCN10ASHMT2PIM1MAPTKDM4E | |
| SCHEMBL2090189 | 0.78 | PIM1 (0.55) | SCN10ASHMT2PIM1MAPTKDM4E | |
| SCHEMBL9264332 | 0.78 | SHMT2 (0.49) | SCN10ASHMT2PIM1MAPTALPI | |
| SCHEMBL23367910 | 0.78 | SCN10A (0.48) | SCN10ASHMT2PIM1MAPTKDM4E | |
| SCHEMBL28817509 | 0.76 | GFER (0.53) | MAPTKDM4EALDH1A1RAB9APOLB | |
| SCHEMBL5396498 | 0.75 | RAB9A (0.50) | MAPTKDM4EALDH1A1RAB9APOLB | |
| SCHEMBL2088997 | 0.75 | SHMT2 (0.61) | SCN10ASHMT2PIM1MAPTKDM4E | |
| SCHEMBL4777890 | 0.75 | SHMT2 (0.58) | SCN10ASHMT2PIM1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104583218-A | Imidazothiadiazole and imidazopyrazine derivatives as protease activated receptor 4(PAR4) inhibitors for the treatment of platelet aggregation | BRISTOL MYERS SQUIBB CO | 2015-04-29 | — | — | CN | disclosed |