Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 4/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26003452 | 0.77 | ALDH1A1 (0.50) | FGFR1NOTUMHPGDSALKBH2KDM4E | |
| SCHEMBL26986724 | 0.74 | ALDH1A1 (0.49) | FGFR1HPGDSALKBH2KDM4EALDH1A1 | |
| SCHEMBL146048 | 0.68 | KDM4E (0.56) | FGFR1NOTUMHPGDSALKBH2KDM4E | |
| Benzoic Acid SCHEMBL108981 | 0.65 | TSHR (0.78) | ALDH1A1HSD17B10POLBMAPTRECQL | |
| SCHEMBL3581132 | 0.65 | SMN1; SMN2 (0.56) | FGFR1NOTUMKDM4EALDH1A1HSD17B10 | |
| SCHEMBL34469977 | 0.63 | NOTUM (0.50) | NOTUMKDM4EALDH1A1MEN1POLB | |
| Terephthalic Acid SCHEMBL11375372 | 0.62 | APOBEC3A (0.61) | ALDH1A1ALOX15DAOTSHRNAPRT | |
| Terephthalic Acid SCHEMBL11371951 | 0.62 | APOBEC3A (0.61) | ALDH1A1ALOX15DAOTSHRNAPRT | |
| Isophthalic Acid SCHEMBL21957749 | 0.62 | APOBEC3A (0.54) | KDM4EALDH1A1HSD17B10MEN1USP2 | |
| Benzoic Acid SCHEMBL16486485 | 0.61 | TSHR (0.93) | ALDH1A1HSD17B10POLBMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105541828-A | Amide imidazole derivative and application thereof | UNIV SHENYANG PHARMACEUTICAL | 2016-05-04 | — | — | CN | disclosed |
| CN-104530038-A | Amide imidazole derivative and application thereof | UNIV SHENYANG PHARMACEUTICAL | 2015-04-22 | — | — | CN | disclosed |