Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2232655 | 0.98 | — | — | |
| SCHEMBL5606250 | 0.98 | — | — | |
| SCHEMBL28323505 | 0.88 | FASN (0.42) | MAPTFFAR1ALDH1A1CYP19A1RXRA | |
| SCHEMBL14161541 | 0.85 | ALDH1A1 (0.59) | MAPTFFAR1ALDH1A1CYP19A1RXRA | |
| SCHEMBL11000998 | 0.84 | FASN (0.52) | MAPTALDH1A1CYP19A1RXRAPPARG | |
| SCHEMBL11001012 | 0.84 | FASN (0.52) | MAPTALDH1A1CYP19A1RXRAPPARG | |
| SCHEMBL28713632 | 0.82 | FASN (0.60) | MAPTFFAR1CYP19A1PPARGOXER1 | |
| SCHEMBL634763 | 0.82 | FASN (0.60) | MAPTFFAR1CYP19A1PPARGOXER1 | |
| SCHEMBL634762 | 0.82 | FASN (0.60) | MAPTFFAR1CYP19A1PPARGOXER1 | |
| SCHEMBL11580318 | 0.82 | ALDH1A1 (0.52) | MAPTFFAR1ALDH1A1CYP19A1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104321431-A | Retro Diels Alder reaction as cleavable linker in DNA/RNA applications | AGILENT TECHNOLOGIES INC | 2015-01-28 | — | — | CN | disclosed |