Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12530631 | 0.90 | CYP19A1 (0.66) | CYP19A1CYP1A2CYP3A4CA12ATM | |
| SCHEMBL12530634 | 0.87 | CYP19A1 (0.62) | CYP19A1CYP1A2CYP3A4CA12ATM | |
| SCHEMBL28113721 | 0.85 | CA12 (0.63) | CYP19A1CYP3A4CA12CA9ALDH1A1 | |
| SCHEMBL3918546 | 0.85 | CYP19A1 (0.68) | CYP19A1ALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL12530468 | 0.84 | KMT2A (0.59) | CYP19A1CYP1A2CYP3A4ALDH1A1MEN1 | |
| SCHEMBL13973371 | 0.84 | CYP19A1 (0.51) | CYP19A1CYP1A2CYP3A4CA12ATM | |
| SCHEMBL25547142 | 0.84 | CA12 (0.83) | CYP19A1CYP1A2CYP3A4CA12ATM | |
| SCHEMBL13959225 | 0.83 | LMNA (0.53) | CYP19A1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL5960116 | 0.83 | MEN1 (0.73) | CYP19A1CYP1A2CYP3A4CA12ATM | |
| SCHEMBL3566649 | 0.82 | CYP19A1 (0.52) | CYP19A1ALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104418678-B | A kind of method of synthetic N-alkyl sulfonamide derivatives | NANJING UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-05-18 | — | — | CN | disclosed |
| CN-104418678-A | Method for synthesizing N-alkyl sulfonamide derivative | UNIV NANJING SCIENCE & TECH | 2015-03-18 | — | — | CN | disclosed |