Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSH | P09668 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12501380 | 0.91 | APEX1 (0.51) | APEX1FBP1ALDH1A1F7F3 | |
| Dimethylformamide SCHEMBL28004370 | 0.86 | APEX1 (0.45) | APEX1FBP1ALDH1A1KDM4ELMNA | |
| SCHEMBL12501410 | 0.83 | KMT2A (0.46) | ALDH1A1KDM4EHPGDHRH4KMT2A | |
| Dimethylformamide SCHEMBL28004366 | 0.80 | HRH4 (0.55) | APEX1ALDH1A1F7F3KDM4E | |
| Dimethylformamide SCHEMBL28004368 | 0.79 | F7 (0.40) | ALDH1A1F7F3KDM4ELMNA | |
| SCHEMBL12501374 | 0.77 | APEX1 (0.51) | APEX1FBP1ALDH1A1KDM4ELMNA | |
| SCHEMBL12501493 | 0.75 | CDK1 (0.49) | ALDH1A1KDM4ELMNAHPGDKMT2A | |
| SCHEMBL12501291 | 0.74 | ALDH1A1 (0.56) | APEX1FBP1ALDH1A1KDM4ELMNA | |
| Dimethylformamide SCHEMBL28003913 | 0.73 | CCR2 (0.39) | ALDH1A1KDM4EHPGDKMT2AGPR35 | |
| SCHEMBL15329178 | 0.72 | HRH4 (0.70) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104334553-A | Amino-indolyl-substituted imidazolyl-pyrimidines and their use as medicaments | BOEHRINGER INGELHEIM INT | 2015-02-04 | — | — | CN | disclosed |