Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27392857 | 0.83 | YTHDC1 (0.63) | YTHDC1KDM4EALDH1A1HTTL3MBTL1 | |
| SCHEMBL5475346 | 0.82 | YTHDC1 (0.40) | YTHDC1KDM4EALDH1A1HTTL3MBTL1 | |
| SCHEMBL28004446 | 0.81 | YTHDC1 (0.41) | YTHDC1KDM4EALDH1A1HTTL3MBTL1 | |
| SCHEMBL28004897 | 0.81 | YTHDC1 (0.41) | YTHDC1KDM4EALDH1A1HTTL3MBTL1 | |
| SCHEMBL21011224 | 0.79 | CDK1 (0.60) | ADORA1CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL28251676 | 0.78 | YTHDC1 (0.66) | YTHDC1ADORA3ADORA1PDE4APDE4B | |
| SCHEMBL28948281 | 0.75 | ADORA2A (0.59) | ALDH1A1ADORA1PDE4APDE4BPDE4C | |
| SCHEMBL28948285 | 0.75 | ADORA2A (0.59) | ALDH1A1ADORA1PDE4APDE4BPDE4C | |
| SCHEMBL28252163 | 0.74 | ADORA3 (0.49) | YTHDC1KDM4EHTTADORA3ADORA1 | |
| SCHEMBL28252137 | 0.72 | CDK1 (0.53) | YTHDC1ALDH1A1HTTADORA1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104447746-A | Compound for activating AMPK and application thereof | HUAAN MEDICAL CO LTD | 2015-03-25 | — | — | CN | claimed |
| CN-108703970-A | Compound for activating AMPK and application thereof | 华安医学股份有限公司 | 2018-10-26 | — | — | CN | disclosed |
| CN-104447746-A | Compound for activating AMPK and application thereof | HUAAN MEDICAL CO LTD | 2015-03-25 | — | — | CN | disclosed |