Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15842754 | 0.84 | KDM4E (0.54) | KDM4EALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL11067092 | 0.79 | KDM4E (0.66) | KDM4EALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL29206918 | 0.79 | KDM4E (0.57) | KDM4EALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL28004955 | 0.79 | ALDH1A1 (0.50) | KDM4EALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL3647430 | 0.79 | KDM4E (0.57) | KDM4EALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL5472418 | 0.77 | HSD17B10 (0.54) | KDM4EALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL5618619 | 0.77 | PDE9A (0.51) | KDM4EALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL10687334 | 0.76 | KDM4E (0.53) | KDM4EALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL11788423 | 0.76 | GAA (0.60) | KDM4EALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL25926071 | 0.74 | KDM4E (0.39) | KDM4EALDH1A1CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104428036-A | Polypeptides and their use | NOVABIOTICS LTD | 2015-03-18 | — | — | CN | disclosed |