Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | NQO1 | P15559 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27628922 | 0.82 | KDM4E (0.62) | HSD17B10KDM4EALDH1A1GAACYP3A4 | |
| SCHEMBL10602111 | 0.82 | HSD17B10 (0.50) | HSD17B10KDM4EALDH1A1GAACYP3A4 | |
| SCHEMBL22780916 | 0.82 | KDM4E (0.58) | HSD17B10KDM4EALDH1A1GAACYP3A4 | |
| SCHEMBL669540 | 0.82 | KDM4E (0.62) | HSD17B10KDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL669541 | 0.82 | KDM4E (0.58) | HSD17B10KDM4EALDH1A1GAACYP3A4 | |
| SCHEMBL30050788 | 0.82 | KDM4E (0.58) | HSD17B10KDM4EALDH1A1GAACYP3A4 | |
| SCHEMBL31178946 | 0.82 | GAA (0.69) | HSD17B10KDM4EALDH1A1GAAMAPT | |
| SCHEMBL28859670 | 0.79 | CA1 (0.51) | HSD17B10KDM4EALDH1A1GAACYP3A4 | |
| SCHEMBL28053823 | 0.79 | CA1 (0.51) | HSD17B10KDM4EALDH1A1GAACYP3A4 | |
| SCHEMBL28004993 | 0.77 | KDM4E (0.50) | HSD17B10KDM4EALDH1A1GAACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070123690-A1 | Conjugated polymers, representation thereof, and use of the same | MERCK PATENT GMBH (DE) | 2007-05-31 | — | — | US | disclosed |