Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13522013 | 0.85 | HTR2A (0.41) | HTR2ACHEK1CCNA2CDK2CCNA1 | |
| SCHEMBL13722653 | 0.85 | CHEK1 (0.36) | HTR2ACHEK1CCNA2CDK2CCNA1 | |
| SCHEMBL15587858 | 0.84 | MAP4K4 (0.41) | HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL9054801 | 0.84 | HTR2A (0.40) | HTR2ACHEK1CCNA2CDK2CCNA1 | |
| SCHEMBL9593395 | 0.82 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23588329 | 0.80 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23578336 | 0.80 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23578374 | 0.80 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9366491 | 0.78 | L3MBTL1 (0.43) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2600249 | 0.76 | HTR2A (0.40) | HTR2AHTR2CCHEK1CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104592215-A | Preparation method of piperidine-substituted oxadiazole derivative | Hunan huateng pharmaceutical co ltd | 2015-05-06 | — | — | CN | disclosed |