SCHEMBL28005394

SCHEMBL28005394

Nc1ccc2c(c1)C(=O)c1ccc(N)cc1C2=O.[GaH3]

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.82
ALDH1A1 P00352 4/20 0.82
RAB9A P51151 4/20 0.82
SMN1; SMN2 Q16637 3/20 0.82
TSHR P16473 3/20 0.82
CYP3A4 P08684 2/20 0.82
MAPK1 P28482 2/20 0.82
TP53 P04637 1/20 0.82
TDP1 Q9NUW8 1/20 0.82
PTPRC P08575 2/20 0.71
LMNA P02545 2/20 0.71
MEN1 O00255 2/20 0.71
KMT2A Q03164 2/20 0.71
APAF1 O14727 1/20 0.71
TDP2 O95551 1/20 0.71
NSD2 O96028 1/20 0.71
PLA2G1B P04054 1/20 0.71
POLB P06746 1/20 0.71
CTSL P07711 1/20 0.71
HPGD P15428 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3135129 0.97 NPC1 (0.86) NPC1ALDH1A1RAB9ASMN1; SMN2TSHR
SCHEMBL9019017 0.92 NPC1 (0.78) NPC1ALDH1A1RAB9ASMN1; SMN2TSHR
SCHEMBL31087632 0.92 NPC1 (0.78) NPC1ALDH1A1RAB9ASMN1; SMN2TSHR
SCHEMBL30350052 0.92 NPC1 (0.77) NPC1ALDH1A1RAB9ASMN1; SMN2TSHR
SCHEMBL9019051 0.92 NPC1 (0.77) NPC1ALDH1A1RAB9ASMN1; SMN2TSHR
SCHEMBL864582 0.92 NPC1 (0.77) NPC1ALDH1A1RAB9ASMN1; SMN2TSHR
Anthraquinone SCHEMBL23363689 0.90 NPC1 (1.00) NPC1ALDH1A1RAB9ASMN1; SMN2TSHR
SCHEMBL31290097 0.90 NPC1 (1.00) NPC1ALDH1A1RAB9ASMN1; SMN2TSHR
SCHEMBL40960 0.90 NPC1 (1.00) NPC1ALDH1A1RAB9ASMN1; SMN2TSHR
Hydrochloric Acid SCHEMBL6938108 0.90 NPC1 (0.74) NPC1ALDH1A1RAB9ASMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104379678-B Water-soluble and water-resistant dyes for ink-jet printing 莱克斯-托恩工业有限公司 2017-07-18 CN disclosed
CN-104379678-A Water-soluble and water-resistant dyes for ink-jet printing ILFORD IMAGING CH GMBH 2015-02-25 CN disclosed