Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.78 |
| ▸ | RAB9A | P51151 | 3/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.78 |
| ▸ | TSHR | P16473 | 2/20 | 0.78 |
| ▸ | TP53 | P04637 | 1/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.78 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.78 |
| ▸ | S100A4 | P26447 | 3/20 | 0.75 |
| ▸ | PTPRC | P08575 | 2/20 | 0.75 |
| ▸ | MEN1 | O00255 | 1/20 | 0.75 |
| ▸ | APAF1 | O14727 | 1/20 | 0.75 |
| ▸ | TDP2 | O95551 | 1/20 | 0.75 |
| ▸ | NSD2 | O96028 | 1/20 | 0.75 |
| ▸ | LMNA | P02545 | 1/20 | 0.75 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.75 |
| ▸ | POLB | P06746 | 1/20 | 0.75 |
| ▸ | CTSL | P07711 | 1/20 | 0.75 |
| ▸ | HPGD | P15428 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31087632 | 1.00 | NPC1 (0.78) | NPC1ALDH1A1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL9019051 | 0.95 | NPC1 (0.77) | NPC1ALDH1A1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL30350052 | 0.95 | NPC1 (0.77) | NPC1ALDH1A1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL3135129 | 0.95 | NPC1 (0.86) | NPC1ALDH1A1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL864582 | 0.95 | NPC1 (0.77) | NPC1ALDH1A1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL28005394 | 0.92 | NPC1 (0.82) | NPC1ALDH1A1RAB9ASMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL6938108 | 0.92 | NPC1 (0.74) | NPC1ALDH1A1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL760965 | 0.91 | NPC1 (0.95) | NPC1ALDH1A1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL31615519 | 0.91 | NPC1 (0.95) | NPC1ALDH1A1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL30482647 | 0.91 | NPC1 (0.95) | NPC1ALDH1A1RAB9ASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8253583-A | — | — | None | — | — | JP | disclosed |
| JP-H08253583-A | POLYIMIDE RESIN MOLDING | FURUKAWA ELECTRIC CO LTD:THE | 1996-10-01 | — | — | JP | disclosed |
| EP-0322586-B1 | Photo-receptor for electrophotography | KONISHIROKU PHOTO IND (JP) | 1994-11-02 | — | — | EP | disclosed |
| US-4939058-A | Durability | KONICA CORPORATION (JP) | 1990-07-03 | — | — | US | disclosed |
| EP-0322586-A2 | Photo-receptor for electrophotography | KONICA CORPORATION (JP) | 1989-07-05 | — | — | EP | disclosed |