SCHEMBL3135129

SCHEMBL3135129

Nc1ccc2c(c1)C(=O)c1cc(N)ccc1C2=O

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.86
ALDH1A1 P00352 4/20 0.86
RAB9A P51151 4/20 0.86
SMN1; SMN2 Q16637 3/20 0.86
TSHR P16473 3/20 0.86
CYP3A4 P08684 2/20 0.86
MAPK1 P28482 2/20 0.86
TP53 P04637 1/20 0.86
TDP1 Q9NUW8 1/20 0.86
PTPRC P08575 2/20 0.74
LMNA P02545 2/20 0.74
MEN1 O00255 2/20 0.74
KMT2A Q03164 2/20 0.74
APAF1 O14727 1/20 0.74
TDP2 O95551 1/20 0.74
NSD2 O96028 1/20 0.74
PLA2G1B P04054 1/20 0.74
POLB P06746 1/20 0.74
CTSL P07711 1/20 0.74
HPGD P15428 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28005394 0.97 NPC1 (0.82) NPC1ALDH1A1RAB9ASMN1; SMN2TSHR
SCHEMBL9019017 0.95 NPC1 (0.78) NPC1ALDH1A1RAB9ASMN1; SMN2TSHR
SCHEMBL31087632 0.95 NPC1 (0.78) NPC1ALDH1A1RAB9ASMN1; SMN2TSHR
SCHEMBL30350052 0.94 NPC1 (0.77) NPC1ALDH1A1RAB9ASMN1; SMN2TSHR
SCHEMBL9019051 0.94 NPC1 (0.77) NPC1ALDH1A1RAB9ASMN1; SMN2TSHR
SCHEMBL864582 0.94 NPC1 (0.77) NPC1ALDH1A1RAB9ASMN1; SMN2TSHR
Anthraquinone SCHEMBL23363689 0.93 NPC1 (1.00) NPC1ALDH1A1RAB9ASMN1; SMN2TSHR
SCHEMBL31290097 0.93 NPC1 (1.00) NPC1ALDH1A1RAB9ASMN1; SMN2TSHR
SCHEMBL40960 0.93 NPC1 (1.00) NPC1ALDH1A1RAB9ASMN1; SMN2TSHR
Hydrochloric Acid SCHEMBL6938108 0.92 NPC1 (0.74) NPC1ALDH1A1RAB9ASMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250118786-A1 LONG-LIVED REDOX-ACTIVE MOLECULES WITH LOW REDOX POTENTIAL HARVARD COLLEGE (US) 2025-04-10 US claimed
CN-119613919-A MXene composite material and preparation method and application thereof 中山大学 2025-03-14 CN claimed
CN-118852700-B Preparation method of high-color-fastness flame-retardant PA66 film and PA66 fiber 江苏新视界先进功能纤维创新中心有限公司 2024-12-31 CN claimed
CN-118852700-A Preparation method of high-color-fastness flame-retardant PA66 film and PA66 fiber 江苏新视界先进功能纤维创新中心有限公司 2024-10-29 CN claimed
CN-118440318-A Anthraquinone-imino polymer and its synthesis and application 武汉大学 2024-08-06 CN claimed
EP-4387954-A1 LONG-LIVED REDOX-ACTIVE MOLECULES WITH LOW REDOX POTENTIAL President and Fellows of Harvard College (US) 2024-06-26 EP claimed
WO-2023023303-A1 LONG-LIVED REDOX-ACTIVE MOLECULES WITH LOW REDOX POTENTIAL PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-02-23 WO claimed
US-20090253709-A1 SYNTHESIS, TELOMERASE INHIBITION AND CYTOTOXIC STUDIES ON 2,7-DISUBSTITUTED ANTHRAQUINONE DERIVATIVES NATIONAL DEFENSE MEDICAL CENTER (TW) 2009-10-08 US claimed
US-7291223-B2 Epitaxial organic layered structure and method for making NITTO DENKO CORPORATION (JP) 2007-11-06 US claimed
JP-2007504305-A 2007-03-01 JP claimed
US-7166161-B2 Anisotropic film manufacturing NITTO DENKO CORPORATION (JP) 2007-01-23 US claimed
US-20050103258-A1 Epitaxial organic layered structure and method for making INSOLVENCY SERVICES GROUP, INC. 2005-05-19 US claimed
WO-2005032217-A1 EPITAXIAL ORGANIC LAYERED STRUCTURE AND METHOD FOR MAKING NITTO DENKO CORPORATION (JP) 2005-04-07 WO claimed
US-20040224182-A1 Backlight polar organic light-emitting device INSOLVENCY SERVICES GROUP, INC. 2004-11-11 US claimed
WO-2004064112-A2 BACKLIGHT POLAR ORGANIC LIGHT-EMITTING DEVICE NITTO DENKO CORPORATION (JP) 2004-07-29 WO claimed
US-20040142183-A1 Anisotropic film manufacturing INSOLVENCY SERVICES GROUP, INC. 2004-07-22 US claimed
EP-0577245-B1 Photogenerating azo pigments XEROX CORP (US) 1998-12-02 EP claimed
US-5281503-A Multilayer element with disazo pigments and charge generating layer XEROX CORPORATION (US) 1994-01-25 US claimed
EP-0577245-A1 Photogenerating azo pigments XEROX CORPORATION (US) 1994-01-05 EP claimed
EP-0406952-A2 Aromatic polymer with diaminoanthraquinone units STAMICARBON B.V. (NL) 1991-01-09 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250118786-A1 LONG-LIVED REDOX-ACTIVE MOLECULES WITH LOW REDOX POTENTIAL GPX4, GPX1, NOX4 NPC1 4346/4885ALDH1A1 326/4885RAB9A 1377/4885
US-20090253709-A1 SYNTHESIS, TELOMERASE INHIBITION AND CYTOTOXIC STUDIES ON 2,7-DISUBSTITUTED ANTHRAQUINONE DERIVATIVES TERT, NAT10, POT1 NPC1 2511/4885ALDH1A1 481/4885RAB9A 1907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.