Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL28264062 | 0.94 | HIF1A (0.39) | HIF1ATDP1TAAR1LMNASLC6A2 | |
| Iodide SCHEMBL1332328 | 0.94 | HIF1A (0.43) | HIF1ATDP1TAAR1LMNASLC6A2 | |
| Iodide SCHEMBL4280211 | 0.94 | HIF1A (0.43) | HIF1ATDP1TAAR1LMNASLC6A2 | |
| Iodide SCHEMBL29937613 | 0.94 | HIF1A (0.43) | HIF1ATDP1TAAR1LMNASLC6A2 | |
| Iodide SCHEMBL42631 | 0.94 | HIF1A (0.43) | HIF1ATDP1TAAR1LMNASLC6A2 | |
| Iodide SCHEMBL17431661 | 0.91 | HIF1A (0.41) | HIF1ATDP1TAAR1LMNASLC6A2 | |
| Phosphine SCHEMBL27994502 | 0.91 | HIF1A (0.41) | HIF1ATDP1TAAR1LMNASLC6A2 | |
| SCHEMBL29371667 | 0.91 | HIF1A (0.45) | HIF1ATDP1TAAR1LMNASLC6A2 | |
| Bromide SCHEMBL28008324 | 0.88 | HIF1A (0.39) | HIF1ATDP1TAAR1LMNASLC6A2 | |
| Fluoride Ion SCHEMBL4615710 | 0.88 | HIF1A (0.43) | HIF1ATDP1TAAR1LMNASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108148394-A | The stable mono-component polyurethane prepreg of storage from urethane composition and thus obtained formed body | 赢创德固赛有限公司 | 2018-06-12 | — | — | CN | claimed |
| CN-103459452-B | Storage-stable polyurethane prepregs made of polyurethane compositions with liquid resin components and molded parts made therefrom | EVONIK DEGUSSA GMBH (DE) | 2016-11-30 | — | — | CN | claimed |
| CN-103012298-B | Benzocyclobutene monomer with triazine ring, preparation method and application | SHANGHAI INST ORGANIC CHEM | 2015-04-01 | — | — | CN | claimed |
| CN-108148394-A | The stable mono-component polyurethane prepreg of storage from urethane composition and thus obtained formed body | 赢创德固赛有限公司 | 2018-06-12 | — | — | CN | disclosed |
| CN-107540813-A | The coating agent of alkoxy silane and allophanic acid ester functional | 赢创德固赛有限公司 | 2018-01-05 | — | — | CN | disclosed |
| CN-107540807-A | Functionalized with alkoxysilane, coating agent containing allophanate | 赢创德固赛有限公司 | 2018-01-05 | — | — | CN | disclosed |
| CN-103459452-B | Storage-stable polyurethane prepregs made of polyurethane compositions with liquid resin components and molded parts made therefrom | EVONIK DEGUSSA GMBH (DE) | 2016-11-30 | — | — | CN | disclosed |
| CN-103210011-B | The method manufacturing the polyurethane-prepreg of stable storing and the profiled member of the urethane composition derived from solution being made from | 赢创德固赛有限公司 | 2016-08-10 | — | — | CN | disclosed |
| CN-105082707-A | Production of fibre composite component part based on aluminium and polyurethane | EVONIK INDUSTRIES AG | 2015-11-25 | — | — | CN | disclosed |
| CN-105082665-A | PRODUCTION OF FIBRE COMPOSITE COMPONENT PART BASED ON STEEL AND POLYURETHANE | EVONIK INDUSTRIES AG | 2015-11-25 | — | — | CN | disclosed |
| CN-102906140-B | The method manufacturing the urethane-prepreg of stable storing and the profiled member be made up of it | EVONIK DEGUSSA GMBH (DE) | 2015-11-25 | — | — | CN | disclosed |
| CN-103012298-B | Benzocyclobutene monomer with triazine ring, preparation method and application | SHANGHAI INST ORGANIC CHEM | 2015-04-01 | — | — | CN | disclosed |