Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL1332328 | 1.00 | HIF1A (0.43) | HIF1ATDP1LMNATSHRALOX12 | |
| Iodide SCHEMBL42631 | 1.00 | HIF1A (0.43) | HIF1ATDP1LMNATSHRALOX12 | |
| Iodide SCHEMBL29937613 | 1.00 | HIF1A (0.43) | HIF1ATDP1LMNATSHRALOX12 | |
| Iodide SCHEMBL17431661 | 0.97 | HIF1A (0.41) | HIF1ATDP1LMNATSHRALOX12 | |
| Phosphine SCHEMBL27994502 | 0.97 | HIF1A (0.41) | HIF1ATDP1LMNATSHRALOX12 | |
| SCHEMBL29371667 | 0.97 | HIF1A (0.45) | HIF1ATDP1LMNATSHRALOX12 | |
| Iodide SCHEMBL28264062 | 0.94 | HIF1A (0.39) | HIF1ATDP1LMNATSHRALOX12 | |
| Iodide SCHEMBL28006013 | 0.94 | HIF1A (0.39) | HIF1ATDP1LMNATSHRALOX12 | |
| Bromide SCHEMBL3076 | 0.93 | HIF1A (0.43) | HIF1ATDP1LMNATSHRALOX12 | |
| SCHEMBL10416287 | 0.93 | HIF1A (0.43) | HIF1ATDP1LMNATSHRALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541499-B2 | Process for the recovery of phosphorus and iodine containing catalyst components | EASTMAN CHEMICAL COMPANY (US) | 2009-06-02 | — | — | US | disclosed |
| US-20070142674-A1 | Process for the recovery of phosphorus and iodine containing catalyst components | JEMSA, LLC | 2007-06-21 | — | — | US | disclosed |
| US-7196227-B2 | Process for the recovery of phosphorus and iodine containing catalyst components | EASTMAN CHEMICAL COMPANY (US) | 2007-03-27 | — | — | US | disclosed |
| EP-1575705-A2 | PROCESS FOR THE RECOVERY OF PHOSPHORUS AND IODINE CONTAINING CATALYST COMPONENTS | EASTMAN CHEMICAL COMPANY (US) | 2005-09-21 | — | — | EP | disclosed |
| US-20040163840-A1 | Process for the recovery of phosphorus and iodine containing catalyst components | EASTMAN CHEMICAL COMPANY | 2004-08-26 | — | — | US | disclosed |
| WO-2004058402-A2 | PROCESS FOR THE RECOVERY OF PHOSPHORUS AND IODINE CONTAINING CATALYST COMPONENTS | EASTMAN CHEMICAL COMPANY (US) | 2004-07-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040163840-A1 | Process for the recovery of phosphorus and iodine containing catalyst components | PPIP5K2, IPMK, PHOSPHO1 | ACHE 188/4885HIF1A 4846/4885TDP1 182/4885 |
| US-20070142674-A1 | Process for the recovery of phosphorus and iodine containing catalyst components | PPIP5K2, IPMK, PHOSPHO1 | ACHE 141/4885HIF1A 4855/4885TDP1 165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.