Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL1332328 | 1.00 | HIF1A (0.43) | HIF1ATDP1LMNATSHRALOX12 | |
| Iodide SCHEMBL4280211 | 1.00 | HIF1A (0.43) | HIF1ATDP1LMNATSHRALOX12 | |
| Iodide SCHEMBL29937613 | 1.00 | HIF1A (0.43) | HIF1ATDP1LMNATSHRALOX12 | |
| Iodide SCHEMBL17431661 | 0.97 | HIF1A (0.41) | HIF1ATDP1LMNATSHRALOX12 | |
| Phosphine SCHEMBL27994502 | 0.97 | HIF1A (0.41) | HIF1ATDP1LMNATSHRALOX12 | |
| SCHEMBL29371667 | 0.97 | HIF1A (0.45) | HIF1ATDP1LMNATSHRALOX12 | |
| Iodide SCHEMBL28264062 | 0.94 | HIF1A (0.39) | HIF1ATDP1LMNATSHRALOX12 | |
| Iodide SCHEMBL28006013 | 0.94 | HIF1A (0.39) | HIF1ATDP1LMNATSHRALOX12 | |
| Bromide SCHEMBL3076 | 0.93 | HIF1A (0.43) | HIF1ATDP1LMNATSHRALOX12 | |
| SCHEMBL10416287 | 0.93 | HIF1A (0.43) | HIF1ATDP1LMNATSHRALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3002 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260109730-A1 | Process For The Preparation Of (3Beta,24S)-25,25,25-Trifluoro-3-Methyl-26,27-Dinorergost-5-ene-3,24-Diol | IND CHIMICA SRL (IT) | 2026-04-23 | — | — | US | claimed |
| EP-4713317-A1 | A PROCESS FOR PURIFICATION OF ETHOFUMESATE | Adama Agan Ltd. (IL) | 2026-03-25 | — | — | EP | claimed |
| US-20260076089-A1 | METHOD FOR MANUFACTURING PHOTOELECTRIC CONVERSION ELEMENT, PHOTOELECTRIC CONVERSION ELEMENT, AND PHOTOELECTRIC CONVERSION MATERIAL | PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) | 2026-03-12 | — | — | US | claimed |
| CN-120040438-A | Isoxazole antiparasitic agents Synthesis method of medicine lotirana | 华南农业大学 | 2025-05-27 | — | — | CN | claimed |
| WO-2024253929-A1 | PROCESSING OF SULFUR SPECIES WITH DEEP EUTECTIC SOLVENTS OR IONIC LIQUIDS | SAUDI ARABIAN OIL COMPANY (SA) | 2024-12-12 | — | — | WO | claimed |
| US-20240399293-A1 | PROCESSING OF SULFUR SPECIES WITH DEEP EUTECTIC SOLVENTS OR IONIC LIQUIDS | SAUDI ARABIAN OIL COMPANY (SA) | 2024-12-05 | — | — | US | claimed |
| WO-2024242064-A1 | METHOD FOR MANUFACTURING PHOTOELECTRIC CONVERSION ELEMENT, PHOTOELECTRIC CONVERSION ELEMENT, AND PHOTOELECTRIC CONVERSION MATERIAL | パナソニックＩＰマネジメント株式会社 | 2024-11-28 | — | — | WO | claimed |
| WO-2024236570-A1 | A PROCESS FOR PURIFICATION OF ETHOFUMESATE | ADAMA AGAN LTD. (IL) | 2024-11-21 | — | — | WO | claimed |
| US-20240287009-A1 | AMINE-FUNCTIONAL MONOMERS AND METHODS OF MAKING SAME | INFINEUM INTERNATIONAL LIMITED (GB) | 2024-08-29 | — | — | US | claimed |
| EP-4410772-A2 | AMINE-FUNCTIONAL MONOMERS AND METHODS OF MAKING SAME | Infineum International Limited (GB) | 2024-08-07 | — | — | EP | claimed |
| EP-0576888-A2 | Process for the preparation of (S)- and (R)-but-3-en-2-ol and their derivatives starting from L- resp. D-lactic acid esters | BOEHRINGER INGELHEIM KG (DE) | 1994-01-05 | — | — | EP | claimed |
| WO-1993004122-A1 | POLYESTER COMPOSITIONS CONTAINING PHOSPHONIUM COMPOUNDS | THE DOW CHEMICAL COMPANY (US) | 1993-03-04 | — | — | WO | claimed |
| US-4841072-A | CATALYTIC CARBOXYLATION OF ALKYLENE OXIDE WITH CARBON DIOXIDE | SCIENTIFIC DESIGN COMPANY, INC. (US) | 1989-06-20 | — | — | US | claimed |
| US-4786741-A | REACTING ALKYLENE OXIDE WITH CARBON DIOXIDE USING A CATALYST | SCIENTIFIC DESIGN COMPANY, INC. (US) | 1988-11-22 | — | — | US | claimed |
| EP-0170986-A2 | A process for the preparation of copolycarbonates of sulfonyl diphenol | MOBAY CORPORATION (US) | 1986-02-12 | — | — | EP | claimed |
| US-4535143-A | QUATERNARY SALTS AND TERTIARY AMINE CATALYSTS; NONEMULSIFICATION MOLECULAR WEIGHT CONTROL, PROCESS | MOBAY CHEMICAL CORPORATION (US) | 1985-08-13 | — | — | US | claimed |
| US-4384126-A | Synthesis of deoxyzoapatanol derivatives | ORTHO PHARMACEUTICAL CORPORATION (US) | 1983-05-17 | — | — | US | claimed |
| US-4333884-A | Production of acetic anhydride | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-06-08 | — | — | US | claimed |
| US-4239689-A | Total synthesis of the utero-evacuant substance d,l-zoapatanol | ORTHO PHARMACEUTICAL CORPORATION (US) | 1980-12-16 | — | — | US | claimed |
| US-3957517-A | Dry stabilization of a silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JA) | 1976-05-18 | — | — | US | claimed |