Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15414500 | 0.82 | SLC2A1 (0.58) | SLC2A1KDM4EHSD17B10XIAPHTT | |
| SCHEMBL4346700 | 0.80 | SLC2A1 (0.50) | SLC2A1KDM4EALDH1A1HPGDGLA | |
| SCHEMBL15414554 | 0.80 | SLC2A1 (0.55) | SLC2A1KDM4EXIAPHTT | |
| SCHEMBL11000179 | 0.78 | ALDH1A1 (0.61) | KDM4EALDH1A1HPGDGLAGAA | |
| Methane SCHEMBL8679956 | 0.77 | ALDH1A1 (0.59) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL5077405 | 0.76 | SLC2A1 (0.51) | SLC2A1KDM4EHPGDHSD17B10HTT | |
| SCHEMBL15414915 | 0.74 | NCEH1 (0.58) | SLC2A1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7333637 | 0.73 | CXCL8 (0.55) | GAATDP1AKR1B1HTT | |
| SCHEMBL2560798 | 0.72 | SLC2A1 (0.48) | SLC2A1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL15414421 | 0.72 | NPC1 (0.62) | SLC2A1KDM4EALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104507913-A | Antiproliferative benzo[b]azepin-2-ones | HOFFMANN LA ROCHE | 2015-04-08 | — | — | CN | disclosed |