Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 8/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28078446 | 0.72 | GLRA1 (0.60) | GLRA1MAOB | |
| SCHEMBL28005978 | 0.72 | GLRA1 (0.43) | GLRA1KDM1AHRH3MAOAMAOB | |
| SCHEMBL28060091 | 0.70 | GLRA1 (0.49) | GLRA1KDM1AMAOAMAOBHTR1A | |
| SCHEMBL28060108 | 0.70 | GLRA1 (0.49) | GLRA1KDM1AMAOAMAOBHTR1A | |
| SCHEMBL19235979 | 0.70 | LMNA (0.38) | SLC6A2 | |
| SCHEMBL28739304 | 0.68 | GLRA1 (0.37) | GLRA1KDM1AHRH3AGTR2 | |
| SCHEMBL9412065 | 0.68 | GLRA1 (0.49) | GLRA1MAOAMAOB | |
| SCHEMBL28739325 | 0.68 | HRH3 (0.35) | GLRA1KDM1AHRH3MAOAMAOB | |
| SCHEMBL28818023 | 0.68 | GLRA1 (0.41) | GLRA1KDM1AHRH3MAOAMAOB | |
| SCHEMBL28818022 | 0.67 | GLRA1 (0.40) | GLRA1HRH3MAOBHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104507898-A | Phenol derivative, preparation method and medical application thereof | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2015-04-08 | — | — | CN | disclosed |