SCHEMBL28006567

SCHEMBL28006567

O=C(O)CC(CO)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.38
TDP1 Q9NUW8 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
GABRR1 P24046 2/20 0.32
LMNA P02545 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MME P08473 2/20 0.32
CACNA2D1 P54289 2/20 0.31
CACNB3 P54284 1/20 0.31
CACNA1C Q13936 1/20 0.31
PGR P06401 1/20 0.31
ADRA1A P35348 1/20 0.31
HTR2B P41595 1/20 0.31
CACNA2D2 Q9NY47 1/20 0.31
OR51E2 Q9H255 1/20 0.31
TSHR P16473 1/20 0.30
FOLH1 Q04609 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8877183 0.87 SLC22A6 (0.43) SLC22A6TDP1SMN1; SMN2GABRR1LMNA
SCHEMBL27823940 0.81 DPP4 (0.37) SLC22A6TDP1SMN1; SMN2GABRR1LMNA
SCHEMBL27464365 0.80 SLC22A6 (0.38) SLC22A6TDP1SMN1; SMN2GABRR1LMNA
SCHEMBL27824024 0.79 TSHR (0.38) SLC22A6TDP1SMN1; SMN2TSHRFOLH1
SCHEMBL1604218 0.78 SLC22A6 (0.36) SLC22A6TDP1SMN1; SMN2GABRR1CACNA2D1
SCHEMBL13560304 0.78 CETP (0.33) TDP1LMNAALDH1A1TSHR
SCHEMBL28474842 0.78 GABRR1 (0.46) SLC22A6TDP1SMN1; SMN2GABRR1LMNA
SCHEMBL27306328 0.76 SLC22A6 (0.35) SLC22A6TDP1SMN1; SMN2GABRR1LMNA
SCHEMBL10717814 0.76 LMNA (0.31) SLC22A6TDP1LMNATSHR
SCHEMBL23829965 0.75 SLC22A6 (0.38) SLC22A6TDP1SMN1; SMN2GABRR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104447416-A Method for preparing 3-tert-butyl oxanamide-4,4,4-trifluoro-methyl butyrate UNIV JILIN 2015-03-25 CN disclosed