Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573362 | 0.79 | HDAC1 (0.37) | — | |
| SCHEMBL918205 | 0.77 | ALDH1A1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL27511908 | 0.75 | ALOX15 (0.41) | BLM | |
| SCHEMBL527878 | 0.73 | — | — | |
| SCHEMBL29107349 | 0.73 | TP53 (0.32) | — | |
| SCHEMBL776175 | 0.72 | TP53 (0.47) | LMNA | |
| SCHEMBL11710261 | 0.72 | TP53 (0.47) | LMNA | |
| SCHEMBL27692090 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL28093135 | 0.71 | — | — | |
| Water SCHEMBL29635525 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104593348-A | FACTOR IX ANALOGUES WITH PROLONGED IN VIVO HALF-LIFE | NOVO NORDISK HEALTHCARE AG | 2015-05-06 | — | — | CN | disclosed |