Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 7/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25564585 | 0.80 | HSD11B1 (0.32) | L3MBTL1PKMHSD11B1HTTKDM4E | |
| SCHEMBL12714 | 0.79 | HSD11B1 (0.48) | L3MBTL1PKMHSD11B1HTTKDM4E | |
| SCHEMBL19557168 | 0.79 | HSD11B1 (0.48) | L3MBTL1PKMHSD11B1HTTKDM4E | |
| SCHEMBL19557166 | 0.79 | HSD11B1 (0.48) | L3MBTL1PKMHSD11B1HTTKDM4E | |
| SCHEMBL17041846 | 0.78 | ALDH1A1 (0.32) | L3MBTL1PKMALDH1A1 | |
| SCHEMBL12219710 | 0.78 | ALDH1A1 (0.36) | L3MBTL1PKMHSD11B1HTTKDM4E | |
| SCHEMBL15827321 | 0.78 | ALDH1A1 (0.36) | L3MBTL1PKMHSD11B1HTTKDM4E | |
| SCHEMBL17547624 | 0.77 | — | — | |
| SCHEMBL4389277 | 0.77 | HSD11B1 (0.46) | L3MBTL1PKMHSD11B1HTTKDM4E | |
| SCHEMBL5489940 | 0.77 | HSD11B1 (0.46) | L3MBTL1PKMHSD11B1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104402883-B | 4,4-difluoro diamantane carboxamides derivatives, pharmaceutical composition and its production and use | Shanghai AQBioPharma Co. Ltd. (CN) | 2016-04-27 | — | — | CN | disclosed |
| CN-104402883-A | 4, 4-difluoroadamantane formamide derivative, pharmaceutical composition, preparation method and application thereof | AIQIKANG MEDICAL TECHNOLOGY SHANGHAI CO LTD | 2015-03-11 | — | — | CN | disclosed |