Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL306964 | 0.82 | CA1 (0.54) | CA1CA2CA12CA7CA9 | |
| SCHEMBL29386813 | 0.82 | CA1 (0.54) | CA1CA2CA12CA7CA9 | |
| SCHEMBL9729192 | 0.79 | KMT2A (0.53) | CA1CA2CA12CA7CA9 | |
| SCHEMBL7288497 | 0.79 | CA1 (0.50) | CA1CA2CA12CA7CA9 | |
| SCHEMBL4554195 | 0.79 | KMT2A (0.53) | CA1CA2CA12CA7CA9 | |
| SCHEMBL4860223 | 0.79 | CA1 (0.50) | CA1CA2CA12CA7CA9 | |
| SCHEMBL28303414 | 0.78 | CA1 (0.48) | CA1CA2CA12CA7CA9 | |
| SCHEMBL7475532 | 0.78 | CA1 (0.48) | CA1CA2CA12CA7CA9 | |
| SCHEMBL27330400 | 0.77 | KMT2A (0.44) | CA1CA2CA12CA7CA9 | |
| 1,2-Dimethoxybenzene SCHEMBL28118612 | 0.77 | CA1 (0.72) | CA1CA2CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102395563-B | Process for the preparation of biphenyl-2-ylcarbamates | GLAXO GROUP LTD | 2015-05-20 | — | — | CN | disclosed |