Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4554195 | 1.00 | KMT2A (0.53) | KMT2ACA1CA2CA12CA4 | |
| SCHEMBL7330787 | 0.85 | IRAK4 (0.59) | KMT2AACHEHTTCXCL8KDM4E | |
| SCHEMBL29386813 | 0.84 | CA1 (0.54) | KMT2ACA1CA2CA12CA4 | |
| SCHEMBL27534818 | 0.84 | KMT2A (0.52) | KMT2ACA1CA2CA12CA4 | |
| SCHEMBL306964 | 0.84 | CA1 (0.54) | KMT2ACA1CA2CA12CA4 | |
| SCHEMBL9321170 | 0.83 | CXCL8 (0.54) | KMT2ACA1CA2POLBL3MBTL1 | |
| SCHEMBL7885098 | 0.82 | PTGS2 (0.64) | KMT2ACA1CA2CA12CA4 | |
| SCHEMBL15695551 | 0.82 | PTGS1 (0.51) | KMT2ACA1CA2CA12CA4 | |
| SCHEMBL8473051 | 0.82 | PTGS2 (0.64) | KMT2ACA1CA2CA12CA4 | |
| SCHEMBL362211 | 0.82 | PTGS2 (0.64) | KMT2ACA1CA2CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102667-A | Antiallergens, antiinflammatory agents, nervous system disorders, immunology, psychological disorders | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |