Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | SCN4A | P35499 | 4/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28007582 | 0.89 | PNMT (0.44) | PNMTSCN4AHTR2AHTR2CNPC1 | |
| SCHEMBL28007525 | 0.82 | PNMT (0.42) | PNMTHTR2AHTR2CNPC1RAB9A | |
| SCHEMBL27895284 | 0.78 | SCN4A (0.52) | PNMTSCN4AHTR2AHTR2CHTR7 | |
| SCHEMBL28818105 | 0.78 | PNMT (0.44) | PNMTHTR2AHTR2CNPC1RAB9A | |
| SCHEMBL28066660 | 0.78 | PNMT (0.49) | PNMTHTR2AHTR2CNPC1RAB9A | |
| SCHEMBL28007527 | 0.77 | PNMT (0.43) | PNMTHTR2AHTR2CNPC1RAB9A | |
| Fluoride SCHEMBL28088547 | 0.76 | CYP1A2 (0.46) | PNMTNPC1RAB9APTGESALOX5 | |
| SCHEMBL28124467 | 0.75 | S1PR5 (0.48) | PNMTHTR2BMEN1KMT2APPARG | |
| SCHEMBL27878314 | 0.74 | PNMT (0.43) | PNMTSCN4AHTR2AHTR2CNPC1 | |
| SCHEMBL3789485 | 0.74 | PNMT (0.42) | PNMTHTR2AHTR2CNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102770408-B | Novel diamine compound and production method thereof | NITTO DENKO CORP | 2015-05-13 | — | — | CN | disclosed |