Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2550157 | 0.81 | ADRA2A (0.54) | PNMTADRA2AADRA2BADRA2CNPC1 | |
| SCHEMBL21951946 | 0.77 | PNMT (0.50) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL28007582 | 0.76 | PNMT (0.44) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL27895284 | 0.76 | SCN4A (0.52) | PNMTHTR7HTR2BHTR2AHTR2C | |
| SCHEMBL28832018 | 0.76 | PNMT (0.52) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL14803713 | 0.75 | PNMT (0.45) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL28066660 | 0.75 | PNMT (0.49) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL895389 | 0.75 | CTSS (0.46) | PNMTADRA2AADRA2BADRA2CNPC1 | |
| SCHEMBL27878411 | 0.74 | PNMT (0.46) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL28007205 | 0.74 | PNMT (0.42) | PNMTNPC1RAB9ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9198985-B2 | Bimodal star polymer architectures as fluorescent and MRI imaging reagents | VANDERBUILT UNIVERSITY (US) | 2015-12-01 | — | — | US | disclosed |
| US-20130029369-A1 | BIMODAL STAR POLYMER ARCHITECTURES AS FLUORESCENT AND MRI IMAGING REAGENTS | NATIONAL SCIENCE FOUNDATION | 2013-01-31 | — | — | US | disclosed |
| WO-2010135666-A1 | BIMODAL STAR POLYMER ARCHITECTURES AS FLUORESCENT AND MRI IMAGING REAGENTS | VANDERBILT UNIVERSITY (US) | 2010-11-25 | — | — | WO | disclosed |