SCHEMBL2800725

SCHEMBL2800725

O=C1c2cc(Br)ccc2-c2ccc(Br)c3cccc1c23

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 2/20 0.63
PTPRC P08575 1/20 0.61
S100A4 P26447 1/20 0.58
KDM4E B2RXH2 1/20 0.49
MAPT P10636 1/20 0.49
PABPC1 P11940 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
CYP1B1 Q16678 9/20 0.48
MCL1 Q07820 1/20 0.46
CYP1A2 P05177 3/20 0.45
MAPK1 P28482 1/20 0.45
ALDH1A1 P00352 1/20 0.44
POLB P06746 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
HKDC1 Q2TB90 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29485718 0.88 CYP1A2 (0.50) BCL2PTPRCS100A4KDM4EMAPT
SCHEMBL2261886 0.88 CYP1A2 (0.50) BCL2PTPRCS100A4KDM4EMAPT
SCHEMBL29698127 0.86 PABPC1 (0.64) PTPRCS100A4KDM4EMAPTPABPC1
SCHEMBL1983882 0.86 PABPC1 (0.64) PTPRCS100A4KDM4EMAPTPABPC1
SCHEMBL17322323 0.86 PABPC1 (0.64) PTPRCS100A4KDM4EMAPTPABPC1
SCHEMBL29907914 0.86 PABPC1 (0.64) PTPRCS100A4KDM4EMAPTPABPC1
SCHEMBL77179 0.84 CYP1B1 (0.61) KDM4EMAPTPABPC1CYP1B1MCL1
SCHEMBL29583035 0.84 CYP1B1 (0.61) KDM4EMAPTPABPC1CYP1B1MCL1
SCHEMBL10350796 0.83 PABPC1 (0.58) PTPRCKDM4EMAPTPABPC1SMN1; SMN2
SCHEMBL17322307 0.81 BCL2 (0.64) BCL2PTPRCS100A4KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104371346-B A kind of vat brown RP dyestuff preparation method 萧县凯奇化工科技有限公司 2016-08-17 CN claimed
CN-104371346-A Method for manufacturing vat brown RP dyestuffs XIAO COUNTY KAIQI CHEMICAL TECHNOLOGY CO LTD 2015-02-25 CN claimed
CN-101492574-B Benzothioxanthene dyes with improved application and toxicological properties CLARIANT INT LTD 2013-02-27 CN claimed
CN-101284949-B New process for synthesizing reduced olive T dye XUZHOU KEDAH FINE CHEMICALS LTD 2010-05-19 CN claimed
CN-100540611-C Reduced olive T (C.I.Vat Black 25) preparation method YABANG CHEMICAL GROUP CO LTD (CN) 2009-09-16 CN claimed
CN-101492574-A Benzothioxanthene dyes with improved application and toxicological properties CLARIANT INT LTD (VG) 2009-07-29 CN claimed
CN-101284949-A New process for synthesizing reduced olive T dye XUZHOU KEDAH FINE CHEMICALS LT (CN) 2008-10-15 CN claimed
US-20230320195-A1 Electroactive Materials LG CHEM, LTD. (KR) 2023-10-05 US disclosed
US-11683979-B2 Electroactive materials LG CHEM, LTD. 2023-06-20 US disclosed
US-11683979-B2 Electroactive materials LG CHEM, LTD. 2023-06-20 US disclosed
US-20180062082-A1 ELECTROACTIVE MATERIALS LG CHEM, LTD. (KR) 2018-03-01 US disclosed
CN-104371346-B A kind of vat brown RP dyestuff preparation method 萧县凯奇化工科技有限公司 2016-08-17 CN disclosed
WO-2016126423-A2 ELECTROACTIVE MATERIALS E I DU PONT DE NEMOURS AND COMPANY (US) 2016-08-11 WO disclosed
EP-2038241-A1 ELECTROLUMINESCENT POLYMERS AND USE THEREOF Merck Patent GmbH (DE) 2009-03-25 EP disclosed
CN-101284949-A New process for synthesizing reduced olive T dye XUZHOU KEDAH FINE CHEMICALS LT (CN) 2008-10-15 CN disclosed
CN-101284949-A New process for synthesizing reduced olive T dye XUZHOU KEDAH FINE CHEMICALS LT (CN) 2008-10-15 CN disclosed
WO-2008006454-A1 ELECTROLUMINESCENT POLYMERS AND USE THEREOF MERCK PATENT GMBH (DE) 2008-01-17 WO disclosed
WO-2008006454-A1 ELECTROLUMINESCENT POLYMERS AND USE THEREOF MERCK PATENT GMBH (DE) 2008-01-17 WO disclosed
US-4323510-A Brown vat dye and its preparation BASF AKTIENGESELLSCHAFT (DE) 1982-04-06 US disclosed
EP-0021075-A1 Process for preparing a vat dyestuff BASF Aktiengesellschaft (DE) 1981-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180062082-A1 ELECTROACTIVE MATERIALS NR4A3, NCOA4, NR4A2 BCL2 4576/4885PTPRC 2594/4885S100A4 136/4885
US-20230320195-A1 Electroactive Materials NR4A3, NCOA4, NR4A2 BCL2 4576/4885PTPRC 2594/4885S100A4 136/4885
US-11683979-B2 Electroactive materials NR4A3, NCOA4, NR4A2 BCL2 4591/4885PTPRC 2533/4885S100A4 139/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.