Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL310511 | 0.98 | LMNA (0.67) | LMNAMAPTKDM4ECYP3A4HSP90AA1 | |
| SCHEMBL28126432 | 0.96 | LMNA (0.65) | LMNAMAPTKDM4ECYP3A4HSP90AA1 | |
| Dipyridyl SCHEMBL29137810 | 0.89 | LMNA (0.56) | LMNAMAPTKDM4ECYP3A4HSP90AA1 | |
| SCHEMBL1003398 | 0.81 | LMNA (0.96) | LMNAMAPTKDM4ECYP3A4HSP90AA1 | |
| SCHEMBL1543407 | 0.81 | LMNA (0.96) | LMNAMAPTKDM4ECYP3A4HSP90AA1 | |
| SCHEMBL3885158 | 0.81 | LMNA (0.96) | LMNAMAPTKDM4ECYP3A4HSP90AA1 | |
| SCHEMBL6903991 | 0.81 | LMNA (0.53) | LMNAMAPTKDM4ECYP3A4HSP90AA1 | |
| SCHEMBL1669125 | 0.80 | LMNA (0.67) | LMNAMAPTKDM4ECYP3A4HSP90AA1 | |
| SCHEMBL8313 | 0.79 | LMNA (1.00) | LMNAMAPTKDM4ECYP3A4HSP90AA1 | |
| SCHEMBL6513577 | 0.79 | LMNA (1.00) | LMNAMAPTKDM4ECYP3A4HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104418915-A | Preparation method and application of complex | CHINA PETROLEUM & CHEMICAL | 2015-03-18 | — | — | CN | disclosed |