Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HIPK2 | Q9H2X6 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ASPH | Q12797 | 1/20 | 0.32 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30411449 | 0.84 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2LMNAHIPK2KDM4E | |
| SCHEMBL23971140 | 0.84 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2LMNAHIPK2KDM4E | |
| SCHEMBL27471803 | 0.83 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2LMNAHIPK2KDM4E | |
| SCHEMBL4793593 | 0.82 | POLB (0.38) | ALDH1A1SMN1; SMN2LMNAHIPK2KDM4E | |
| SCHEMBL3223703 | 0.79 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2LMNADAOHTT | |
| SCHEMBL31713579 | 0.79 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2LMNADAOHTT | |
| SCHEMBL1563112 | 0.78 | ATR (0.47) | ALDH1A1LMNAKDM4EATRKDM4C | |
| SCHEMBL30047616 | 0.76 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2LMNAKDM4EASPH | |
| SCHEMBL12931889 | 0.76 | HTT (0.39) | ALDH1A1SMN1; SMN2LMNAHIPK2HTT | |
| SCHEMBL10561174 | 0.76 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2LMNAEGFRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104910148-B | Aminotriazole(ATA) and pyridine and its as kinase inhibitor purposes | 西格诺药品有限公司 | 2017-06-27 | — | — | CN | disclosed |
| CN-104910148-A | Aminotriazolopyridines and use thereof as kinase inhibitors | SIGNAL PHARM LLC | 2015-09-16 | — | — | CN | disclosed |
| CN-102203093-B | Aminotriazolopyridines and their use as kinase inhibitors | SIGNAL PHARM LLC | 2015-05-13 | — | — | CN | disclosed |