Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 8/20 | 0.36 |
| ▸ | JAK2 | O60674 | 7/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31713579 | 1.00 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2LMNAPTGESHTT | |
| SCHEMBL31713567 | 0.83 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2LMNAPTGESHTT | |
| SCHEMBL392396 | 0.83 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2LMNAPTGESHTT | |
| SCHEMBL27471803 | 0.83 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2LMNAHTTPOLB | |
| SCHEMBL2159768 | 0.81 | POLB (0.40) | ALDH1A1SMN1; SMN2LMNAPTGESHTT | |
| SCHEMBL382884 | 0.81 | TYK2 (0.39) | ALDH1A1SMN1; SMN2LMNAPTGESHTT | |
| Hydrochloric Acid SCHEMBL9355662 | 0.81 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2LMNAPTGESHTT | |
| SCHEMBL30765091 | 0.81 | TYK2 (0.39) | ALDH1A1SMN1; SMN2LMNAPTGESHTT | |
| SCHEMBL30674019 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TYK2JAK2GAAJAK1 | |
| SCHEMBL26941587 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TYK2JAK2GAAJAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113004196-A | N- (benzyloxy) -2-chloronicotinamides compound and preparation method and application thereof | 浙江工业大学 | 2021-06-22 | — | — | CN | claimed |
| EP-0446872-B1 | Process for the preparation of 2,3-dichloro-5-acetylpyridine | LONZA AG (CH) | 1994-09-21 | — | — | EP | claimed |
| US-20250206755-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2025-06-26 | — | — | US | disclosed |
| CN-117510338-A | Natural naphthoquinone derivative and preparation method and application thereof | 贵州大学 | 2024-02-06 | — | — | CN | disclosed |
| WO-2023235305-A2 | SULFONYL CYCLIC DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | Lysoway Therapeutics, Inc. (US) | 2023-12-07 | — | — | WO | disclosed |
| WO-2023199938-A1 | NOVEL PYRIDINIUM COMPOUND | 花王株式会社 | 2023-10-19 | — | — | WO | disclosed |
| WO-2023109120-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |
| EP-4192816-A1 | COMPOUNDS AS C5AR INHIBITORS | Kira Pharmaceuticals (Suzhou) Ltd. (CN) | 2023-06-14 | — | — | EP | disclosed |
| CN-113004196-B | N- (benzyloxy) -2-chloronicotinamides compound and preparation method and application thereof | 浙江工业大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-113004196-B | N- (benzyloxy) -2-chloronicotinamides compound and preparation method and application thereof | 浙江工业大学 | 2022-05-13 | — | — | CN | disclosed |
| US-11129814-B2 | Antimicrobial agents | TAXIS PHARMACEUTICALS, INC. (US) | 2021-09-28 | — | — | US | disclosed |
| WO-2003080576-A2 | PYRIDINYL AMIDES AND COMPOSITIONS THEREOF FOR USE AS FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-10-02 | — | — | WO | disclosed |
| EP-1322614-A2 | PYRIDINYL AMIDES AND IMIDES FOR USE AS FUNGICIDES | E. I. du Pont de Nemours and Company (US) | 2003-07-02 | — | — | EP | disclosed |
| CN-1391476-A | Vasopressin agonist formulation and process | AMERICAN CYANAMID CO (US) | 2003-01-15 | — | — | CN | disclosed |
| WO-2002022583-A2 | PYRIDINYL AMIDES AND IMIDES FOR USE AS FUNGICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-03-21 | — | — | WO | disclosed |
| EP-1140905-A1 | HETEROAROMATIC AMIDES AS INHIBITOR OF FACTOR XA | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| EP-1114045-A1 | 2-METHOXYIMINO-2-(PYRIDINYLOXYMETHYL)PHENYL ACETAMIDES WITH 5 MEMBERED HETEROCYCLIC RINGS ON THE PYRIDINE RING AS FUNGICIDES | Dow AgroSciences LLC (US) | 2001-07-11 | — | — | EP | disclosed |
| WO-2000039117-A1 | HETEROROAROMATIC AMIDES AS INHIBITOR OF FACTOR Xa | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |
| WO-2000015637-A1 | 2-METHOXYIMINO -2-(PYRIDINYLOXYMETHYL) PHENYL ACETAMIDES WITH 5 MEMBERED HETEROCYCLIC RINGS ON THE PYRIDINE RING AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2000-03-23 | — | — | WO | disclosed |
| US-5166352-A | Pyridinecarboxylic acid chlorides from (trichloromethyl)pyridines | DOWELANCO (US) | 1992-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11129814-B2 | Antimicrobial agents | MRPL21, SPOUT1, LSS | ALDH1A1 3512/4885SMN1; SMN2 4451/4885LMNA 2883/4885 |
| US-20250206755-A1 | ANTIMICROBIAL AGENTS | CFTR, MRPL21, ARG1 | ALDH1A1 1945/4885SMN1; SMN2 2119/4885LMNA 2434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.