Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA6 | P23280 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8205330 | 0.83 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2LMNACA1 | |
| SCHEMBL29126658 | 0.79 | TSHR (0.40) | NPC1RAB9ASMN1; SMN2LMNACA1 | |
| SCHEMBL10824823 | 0.78 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2LMNACA1 | |
| SCHEMBL18014872 | 0.76 | HCAR2 (0.41) | NPC1RAB9ASMN1; SMN2LMNAPTGS1 | |
| SCHEMBL14479079 | 0.76 | HMGCR (0.41) | NPC1RAB9ASMN1; SMN2LMNAPTGS1 | |
| SCHEMBL11613545 | 0.76 | PTGS1 (0.34) | NPC1RAB9ASMN1; SMN2LMNACA1 | |
| SCHEMBL2177295 | 0.76 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2LMNACA1 | |
| SCHEMBL17294310 | 0.76 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2LMNACA1 | |
| SCHEMBL18014878 | 0.75 | HCAR2 (0.43) | NPC1RAB9ASMN1; SMN2LMNACA1 | |
| SCHEMBL18014854 | 0.75 | HCAR2 (0.39) | NPC1RAB9ASMN1; SMN2LMNACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102639509-B | Azole derivative, process for producing the same, intermediate of the same, and agricultural or horticultural agent | KUREHA CORP. (JP) | 2016-03-23 | — | — | CN | disclosed |
| CN-104672092-A | Azole derivatives, methods for producing the same, intermediate thereof, agro-horticultural agents | KUREHA CORP | 2015-06-03 | — | — | CN | disclosed |
| CN-104610235-A | AZOLE DERIVATIVES, METHODS FOR PRODUCING THE SAME, INTERMEDIATE THEREOF, AGRO-HORTICULTURAL AGENTS | KUREHA CORP | 2015-05-13 | — | — | CN | disclosed |