Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | DHPS | P49366 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3370022 | 0.86 | DPP4 (0.72) | DPP4 | |
| SCHEMBL3372212 | 0.79 | DPP4 (0.78) | DPP4 | |
| SCHEMBL3369971 | 0.72 | DPP4 (0.75) | DPP4 | |
| SCHEMBL3369228 | 0.70 | DPP4 (1.00) | DPP4 | |
| SCHEMBL7616076 | 0.70 | ALDH1A1 (0.58) | HTT | |
| SCHEMBL3369578 | 0.70 | DPP4 (1.00) | DPP4 | |
| SCHEMBL3369473 | 0.69 | DPP4 (1.00) | DPP4 | |
| SCHEMBL9566448 | 0.69 | KDM4E (0.58) | HTT | |
| SCHEMBL8489079 | 0.69 | KDM4E (0.58) | HTT | |
| SCHEMBL3369334 | 0.69 | DPP4 (0.77) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532037-B | Novel pyrimidine derivatives as well as preparation method and applications thereof | SHANGHAI INST PHARM INDUSTRY | 2015-05-20 | — | — | CN | disclosed |