Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | DHFR | P00374 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | GFER | P55789 | 2/20 | 0.51 |
| ▸ | MPI | P34949 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566448 | 0.96 | KDM4E (0.58) | KDM4EHSD17B10DHFRALDH1A1TDP1 | |
| SCHEMBL7616076 | 0.90 | ALDH1A1 (0.58) | KDM4EHSD17B10ALDH1A1TDP1GAA | |
| SCHEMBL9566413 | 0.82 | HRH4 (0.66) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL5031343 | 0.82 | RAB9A (0.57) | KDM4EHSD17B10ALDH1A1GAAMEN1 | |
| SCHEMBL5066542 | 0.82 | NPC1 (0.54) | KDM4EALDH1A1GAAGFERADORA1 | |
| SCHEMBL1388381 | 0.79 | DYRK1A (0.66) | KDM4EHSD17B10DHFRALDH1A1GAA | |
| SCHEMBL7140279 | 0.78 | ALDH1A1 (0.59) | KDM4EHSD17B10ALDH1A1TDP1GAA | |
| SCHEMBL30610431 | 0.78 | ALDH1A1 (0.59) | KDM4EHSD17B10ALDH1A1TDP1GAA | |
| SCHEMBL2180788 | 0.77 | L3MBTL1 (0.53) | KDM4EHSD17B10ALDH1A1TDP1GAA | |
| SCHEMBL7708794 | 0.77 | KDM4E (0.54) | KDM4EHSD17B10ALDH1A1TDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999011633-A1 | TRIAZINES WITH AN ADENOSINE ANTAGONISTIC EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-03-11 | — | — | WO | disclosed |