SCHEMBL28007680

SCHEMBL28007680

O=C(c1ccccc1)C(Cc1ccccc1)[N+](=O)[O-]

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MDM2 Q00987 1/20 0.58
CPA1 P15085 6/20 0.50
CYP1A2 P05177 1/20 0.44
NPC1 O15118 1/20 0.43
TP53 P04637 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
ALPI P09923 1/20 0.42
PKM P14618 1/20 0.42
PTGS1 P23219 1/20 0.42
XIAP P98170 1/20 0.42
SLC7A5 Q01650 1/20 0.42
ALPL P05186 1/20 0.41
POLB P06746 1/20 0.41
ALPG P10696 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
CTRB1 P17538 2/20 0.41
CTNNB1 P35222 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2555562 0.84 CPA1 (0.59) CPA1CYP1A2ALPIPKMPTGS1
SCHEMBL11765684 0.82 MDM2 (0.43) MDM2CPA1TP53CTNNB1
SCHEMBL11081087 0.82 CPA1 (0.53) MDM2CPA1CYP1A2NPC1TP53
SCHEMBL1305447 0.81 CPA1 (0.51) MDM2CPA1CYP1A2NPC1TP53
SCHEMBL11856157 0.81 CPA1 (0.51) MDM2CPA1CYP1A2ALPIPKM
SCHEMBL25423192 0.81 PGR (0.46) MDM2NPC1RAB9AALDH1A1MAPT
SCHEMBL5738139 0.81 TSHR (0.44) MDM2CYP1A2ALDH1A1CTNNB1
SCHEMBL31453476 0.78 ALDH1A1 (0.49) CYP1A2NPC1RAB9AALDH1A1CTNNB1
SCHEMBL11608490 0.78 PTPN1 (0.40) MDM2CPA1NPC1RAB9ASMN1; SMN2
SCHEMBL11612169 0.78 MAPK1 (0.40) MDM2CPA1NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104387277-A Method for synthesizing 2-nitro-3-phenyl propiophenone UNIV CHANGZHOU 2015-03-04 CN claimed
CN-104387277-A Method for synthesizing 2-nitro-3-phenyl propiophenone UNIV CHANGZHOU 2015-03-04 CN disclosed
CN-104387277-A Method for synthesizing 2-nitro-3-phenyl propiophenone UNIV CHANGZHOU 2015-03-04 CN disclosed
CN-104387277-A Method for synthesizing 2-nitro-3-phenyl propiophenone UNIV CHANGZHOU 2015-03-04 CN disclosed