SCHEMBL28007692

SCHEMBL28007692

C=C(Cn1c2ccccc2c2ccccc21)C(C)=O

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.59
TSPO P30536 4/20 0.54
GLA P06280 1/20 0.50
POLB P06746 1/20 0.48
FABP4 P15090 3/20 0.47
FABP5 Q01469 3/20 0.47
FABP3 P05413 1/20 0.47
CYP1A2 P05177 1/20 0.45
CYP2C19 P33261 1/20 0.45
HDAC6 Q9UBN7 1/20 0.44
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
BACE1 P56817 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27151558 0.82 KDM4E (0.59) KDM4ETSPOGLAPOLBFABP4
SCHEMBL31567562 0.82 KDM4E (0.59) KDM4ETSPOGLAPOLBFABP4
SCHEMBL15356177 0.81 KDM4E (0.57) KDM4ETSPOGLAPOLBFABP4
SCHEMBL1128466 0.81 KDM4E (0.68) KDM4ETSPOGLAPOLBFABP4
SCHEMBL4928090 0.80 TSPO (0.56) KDM4ETSPOALDH1A1HPGDNPSR1
SCHEMBL14003754 0.77 KDM4E (0.73) KDM4ETSPOGLAPOLBFABP4
SCHEMBL14003751 0.77 KDM4E (0.73) KDM4ETSPOGLAPOLBFABP4
SCHEMBL28165495 0.77 KDM4E (0.61) KDM4ETSPOGLAPOLBFABP4
SCHEMBL29859932 0.75 KDM4E (1.00) KDM4ETSPOGLAPOLBFABP4
SCHEMBL150053 0.75 KDM4E (1.00) KDM4ETSPOGLAPOLBFABP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104447506-A Preparation method of 2-acetyl-9-alkyl carbazole QINGHAI INST SALT LAKES CAS 2015-03-25 CN claimed
CN-104447506-A Preparation method of 2-acetyl-9-alkyl carbazole QINGHAI INST SALT LAKES CAS 2015-03-25 CN disclosed