Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDIA6 | Q15084 | 1/20 | 0.34 |
| ▸ | DUT | P33316 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9934246 | 0.87 | KDM4E (0.32) | PDIA6DUT | |
| SCHEMBL28008529 | 0.85 | FFAR1 (0.37) | PDIA6CA12CA1CA2TSHR | |
| SCHEMBL28008160 | 0.83 | PDIA6 (0.37) | PDIA6CA12CA1CA2TSHR | |
| SCHEMBL9934856 | 0.82 | PDIA6 (0.36) | PDIA6DUT | |
| SCHEMBL28008145 | 0.82 | SYK (0.34) | PDIA6CA12CA1CA2TSHR | |
| SCHEMBL9935694 | 0.80 | — | — | |
| SCHEMBL28035468 | 0.79 | ALDH1A1 (0.42) | PDIA6 | |
| SCHEMBL27793390 | 0.77 | TSHR (0.41) | CA12CA1CA2TSHRCA7 | |
| SCHEMBL28008191 | 0.76 | PDE3B (0.44) | — | |
| SCHEMBL27999329 | 0.75 | MAPT (0.39) | CA12CA1CA2TSHRCA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104710381-A | Novel 3-hydroxy-5-arylisothiazole derivative | MOCHIDA PHARM CO LTD | 2015-06-17 | — | — | CN | disclosed |
| CN-102712610-B | Novel 3-hydroxy-5-arylisothiazole derivatives | MOCHIDA PHARM CO LTD | 2015-03-04 | — | — | CN | disclosed |