Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 20/20 | 0.46 |
| ▸ | GNA15 | P30679 | 1/20 | 0.38 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.38 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.38 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.38 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30441627 | 0.80 | FFAR1 (0.61) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL28008139 | 0.78 | RARB (0.36) | FFAR1 | |
| SCHEMBL28008148 | 0.77 | FFAR1 (0.40) | FFAR1 | |
| SCHEMBL28008107 | 0.75 | FFAR1 (0.35) | FFAR1 | |
| SCHEMBL18471244 | 0.74 | FFAR1 (0.45) | FFAR1 | |
| SCHEMBL27997690 | 0.73 | FFAR1 (0.33) | FFAR1 | |
| SCHEMBL18518617 | 0.73 | PDIA6 (0.46) | FFAR1 | |
| SCHEMBL13518802 | 0.73 | FFAR1 (0.44) | FFAR1 | |
| SCHEMBL27913199 | 0.72 | FFAR1 (0.59) | FFAR1 | |
| SCHEMBL16523399 | 0.72 | FFAR1 (0.65) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104710381-A | Novel 3-hydroxy-5-arylisothiazole derivative | MOCHIDA PHARM CO LTD | 2015-06-17 | — | — | CN | claimed |
| CN-102712610-B | Novel 3-hydroxy-5-arylisothiazole derivatives | MOCHIDA PHARM CO LTD | 2015-03-04 | — | — | CN | claimed |
| CN-105001219-A | Novel cyclic azabenzimidazole derivatives useful as anti-diabetic agents | MERCK SHARP & DOHME | 2015-10-28 | — | — | CN | disclosed |
| CN-104710381-A | Novel 3-hydroxy-5-arylisothiazole derivative | MOCHIDA PHARM CO LTD | 2015-06-17 | — | — | CN | disclosed |
| CN-104684907-A | Antidiabetic tricyclic compounds | MERCK SHARP & DOHME | 2015-06-03 | — | — | CN | disclosed |
| CN-102712610-B | Novel 3-hydroxy-5-arylisothiazole derivatives | MOCHIDA PHARM CO LTD | 2015-03-04 | — | — | CN | disclosed |