Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 12/20 | 0.40 |
| ▸ | NCF1 | P14598 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28008532 | 0.80 | NCF1 (0.35) | FFAR1NCF1MEN1KMT2AKDM4E | |
| SCHEMBL28008107 | 0.78 | FFAR1 (0.35) | FFAR1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL30833000 | 0.78 | FFAR1 (0.55) | FFAR1NCF1MEN1KMT2ATAAR1 | |
| SCHEMBL28008153 | 0.77 | FFAR1 (0.46) | FFAR1 | |
| SCHEMBL1070016 | 0.71 | CYP1A2 (0.38) | — | |
| SCHEMBL2449865 | 0.71 | L3MBTL1 (0.38) | NCF1MEN1KMT2ATAAR1KDM4E | |
| SCHEMBL3741319 | 0.70 | ACACB (0.43) | FFAR1MEN1KMT2A | |
| SCHEMBL28008147 | 0.69 | FFAR1 (0.53) | FFAR1MAPK1 | |
| SCHEMBL15219240 | 0.69 | NCF1 (0.49) | NCF1MEN1KMT2ATAAR1KDM4E | |
| SCHEMBL3631558 | 0.69 | ALDH1A1 (0.46) | FFAR1NCF1MEN1KMT2ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104710381-A | Novel 3-hydroxy-5-arylisothiazole derivative | MOCHIDA PHARM CO LTD | 2015-06-17 | — | — | CN | claimed |
| CN-102712610-B | Novel 3-hydroxy-5-arylisothiazole derivatives | MOCHIDA PHARM CO LTD | 2015-03-04 | — | — | CN | claimed |
| CN-104710381-A | Novel 3-hydroxy-5-arylisothiazole derivative | MOCHIDA PHARM CO LTD | 2015-06-17 | — | — | CN | disclosed |
| CN-102712610-B | Novel 3-hydroxy-5-arylisothiazole derivatives | MOCHIDA PHARM CO LTD | 2015-03-04 | — | — | CN | disclosed |