Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 2/20 | 0.44 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2012719 | 0.81 | GRM5 (0.53) | BTKNPSR1RXFP1GRM5IKBKB | |
| SCHEMBL22468488 | 0.79 | BTK (0.46) | BTKNPSR1RXFP1GRM5SQOR | |
| SCHEMBL8815555 | 0.79 | NPSR1 (0.47) | BTKNPSR1RXFP1GRM5SQOR | |
| SCHEMBL12828418 | 0.77 | KDM4E (0.45) | MAPTHTTBRD4LMNARAB9A | |
| SCHEMBL22468497 | 0.77 | BTK (0.58) | BTKNPSR1RXFP1GRM5IKBKB | |
| SCHEMBL29899091 | 0.77 | GRM5 (0.49) | BTKNPSR1RXFP1GRM5SQOR | |
| SCHEMBL27491920 | 0.75 | GRM5 (0.48) | BTKNPSR1RXFP1GRM5SQOR | |
| SCHEMBL997865 | 0.75 | GRM5 (0.64) | BTKNPSR1RXFP1GRM5CSNK1A1 | |
| SCHEMBL31249984 | 0.75 | GRM5 (0.64) | BTKNPSR1RXFP1GRM5CSNK1A1 | |
| SCHEMBL29506339 | 0.75 | GRM5 (0.64) | BTKNPSR1RXFP1GRM5CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104540825-A | Azaindolines | HOFFMANN LA ROCHE | 2015-04-22 | — | — | CN | disclosed |